![Squamous Cell Cancer-Head/Neck](https://is1-ssl.mzstatic.com/image/thumb/Purple125/v4/3b/b6/b1/3bb6b108-38df-eead-9d1e-9f5df4e2d3ea/AppIcon-0-0-1x_U007emarketing-0-0-0-7-0-0-sRGB-0-0-0-GLES2_U002c0-512MB-85-220-0-0.png/256x256bb.jpg)
Squamous Cell Cancer-Head/Neck
iOS Universel / Education
Squamous cell carcinomas of the head and neck (SCCHN) are a group of cancers that develop from a thin, moist layer of squamous cells—called a mucosal surface—that line the inner structures of the head and neck, such as the mouth, nose, and throat. Cancer cells use a variety of ways to avoid the body’s natural defense—the immune system—to continue to grow, invade, and spread. In SCCHN, molecular interactions between PD-1 on our immune system’s T-cells and PD-L1 on cancer cells drive whether or not the body’s immune system will attack a cancer cell. This program will look at the cellular underpinnings of SCCHN, as well as agents—known as checkpoint inhibitors—that target PD-1 or PD-L1 for improved management of this condition.
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